Good point Justin! Veeam works great but doesn’t provide mailbox- or item-level restore, but we weren’t doing that anyway. I’m contemplating setting up a script with PowerShell to export mailboxes to PST on a regular basis for that reason for us. For now, deleted item retention (which is better and more thorough in Exchange 2010 already) should provide most of what we need, and then the backups are disaster-recovery only. I haven’t tried Windows Image Backups in Exchange 2010 yet, but I know they were working in Exchange 2007 as of Service Pack 2 (before that, Exchange 2007 on Server 2008 had no built-in backup options that were VSS aware, although on Server 2003 NTBackup still worked).

With Veeam Backup 4’s new support for the Changed Block Tracking in vSphere, my daily Exchange backups are taking less than a half-hour (sometimes even 15 minutes) and are pulling from the SAN directly. I’m contemplating increasing the frequency to occur even more often.